Download Advances in Parasitology, Vol. 66 by David Rollinson, S.I. Hay PDF

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By David Rollinson, S.I. Hay

First released in 1963, Advances in Parasitology comprises accomplished and updated stories in all parts of curiosity in modern parasitology. Advances in Parasitology comprises clinical reviews on parasites of significant impact, comparable to Plasmodium falciparum and trypanosomes. The sequence additionally comprises experiences of extra conventional components, equivalent to zoology, taxonomy, and existence heritage, which form present pondering and functions. Eclectic volumes are supplemented through thematic volumes on a number of themes together with distant Sensing and Geographical info structures in Epidemiology and The Evolution of Parasitism--A phylogenetic persepective.

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Extra info for Advances in Parasitology, Vol. 66

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Occurs more frequently with temperate region strains than it does with tropical strains . . true latency occurs only when the sporozoites injected are too few to set up an immediate attack’; however, with patients seemingly recovered from Madagascar-strain infections, ‘if they were infected with a different strain of the same species, some developed fever and parasites but with a protracted incubation period, usually of several months duration’ (Shute, 1946). Initial latency might be influenced not only by dose, and parasite strain, but individual host response: ‘the time which elapses between the date of being bitten by an infected mosquito and the date when the earliest clinical symptoms are felt by the patient varies with the dose of sporozoites injected, the virulence of the particular strain of parasite, and the different factors which tend to lessen or to increase the patient’s resisting power’ (James, 1920).

G. infectivity). Aside from the limited experience of malariatherapy and laboratory experiments, the existence of a strain may be too transient for any definition to be useful. Therefore, it is unclear whether increasingly detailed genetic identification 34 F. Ellis McKenzie et al. of strains will ever converge with the clinical definition of strains pioneered during the 1920s–1970s. The idea that each of the species that cause human malaria consists of ‘varieties, strains or races’ emerged from the observation that malaria infections seemed to differ in severity from place to place and the inference that these differences might arise from biological differences between morphologically identical parasites.

1993), but the high frequency of recombination during the sexual phase of the parasite life-cycle (confirming that ‘male gametocytes of one strain’ can indeed ‘fertilize the females of a different strain’) may mean that outcrossing, between strains, is as common as ‘selfing’ and thus, as predicted by Shute and Maryon (1954), that strains rapidly lose their identity in endemic areas. Hence, as with drug response, the role of infectivity in maintaining and characterizing strains began to appear highly complex.

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